Our dental practice is now pleased to accelerate your recovery from
numbness after routine dental procedures. OraVerse™ is the first and
only product of its kind to rapidly reverse the effects of local
anesthetics containing a vasoconstrictor so you can feel, speak, smile,
and drink normally in approximately half the time.1 OraVerse is not
recommended for use in children less than 6 years of age or weighing
less than 15 kg (33 lbs).
For more information on this innovative new product, we invite you to
visit the OraVerse Website.
Important Safety Information
Tachycardia, bradycardia, and cardiac arrhythmias may occur with the use
of phentolamine or other alpha-adrenergic blocking agents. Although such
effects are uncommon with OraVerse (phentolamine mesylate), clinicians
should be alert to the signs and symptoms of these events, particularly
in patients with a history of cardiovascular disease. Following
parenteral use of phentolamine at doses between 5 to 15 times higher
than the recommended dose of OraVerse, myocardial infarction, and
cerebrovascular spasm and occlusion have been reported, usually in
association with marked hypotensive episodes producing shock-like
states.
1 Median time to recovery of normal sensation was reduced by 85 minutes
(55%) in the mandible and by 83 minutes (62%) in the maxilla compared to
control. Median time to recovery of normal function was reduced by 60
minutes (50%) in the mandible and by 45 minutes (43%) in the maxilla.